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That said, a closer look at the trend reveals a steep decline in the number of adults who were current smokers from 1985 through 1990, a slight increase in 1991-1992, and a relatively flat, although downward-sloping, curve from 1992 through 2005, as illustrated in Figure 1-2 (CDC 2006b

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Varenicline: an alpha4beta2 nicotinic receptor partial agonist for smoking cessation